Date of Completion

Spring 5-12-2013

Thesis Advisor(s)

Fotios Papadimitrakopoulos

Honors Major

Molecular and Cell Biology

Disciplines

Cell Biology | Molecular Biology

Abstract

Implantable glucose sensors for Diabetes management should possess several attributes such as linearity, sensitivity, selectivity, long life time and should elicit no negative tissue response. Based on this, the UConn implantable glucose sensor team has developed a 5-layer sensor architecture that simultaneously affords the aforementioned requirements. However, the large scale production of these 5-layer sensors is inhibited by the lack of high sensor-to-sensor reproducibility. Herein, we investigate the origin of sensor-to-sensor irreproducibility and develop methodologies for large-scale fabrication of these devices.

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