Glucose Biosensor Using Electrospun Mn2O3-Ag Nanofibers

Authors

Shan HuangFollow

Date of Completion

8-22-2011

Embargo Period

8-22-2011

Advisors

Baikun Li; William Mustain

Field of Study

Biomedical Engineering

Degree

Master of Science

Open Access

Open Access

Abstract

The highly porous Mn₂O₃-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination) and then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. A notable enhancement of direct electron transfer between GOD and the electrode is observed at the Mn₂O₃-Ag-GOD modified electrode with a fast electron transfer rate constant. The biosensor also shows fast response to glucose, high sensitivity (40.60 μA×mM^-1×cm^-2), low detection limit (1.73 µM at S/N=3), low K_m,app value and excellent selectivity. These results indicate that the novel Mn₂O₃-Ag nanfibers-GOD composite has great potential application in oxygen-reduction-based glucose biosensing.

Recommended Citation

Huang, Shan, "Glucose Biosensor Using Electrospun Mn2O3-Ag Nanofibers" (2011). Master's Theses. 147.
https://digitalcommons.lib.uconn.edu/gs_theses/147

Major Advisor

Yu Lei