Title
Investigation of the asymmetric Doering-Moore-Skattebol synthesis of allenes and carbolithiation methodologies
Date of Completion
January 2010
Keywords
Chemistry, Organic
Degree
Ph.D.
Abstract
The asymmetric Doering-Moore-Skattebøl synthesis of allenes has been investigated. A modest enantioselectivity was observed in the presence of (−)-sparteine as a chiral ligand. Kinetic resolution of racemic 1,2-cyclononadiene was observed under certain conditions. An intramolecular carbolithiation route to all isomeric azaindolines was developed by the cyclization of aryllithiums derived from (N,N-diallylamino)bromopyridines. ^
Recommended Citation
Sharma, Vijayata, "Investigation of the asymmetric Doering-Moore-Skattebol synthesis of allenes and carbolithiation methodologies" (2010). Doctoral Dissertations. AAI3415562.
https://digitalcommons.lib.uconn.edu/dissertations/AAI3415562