Date of Completion
5-4-2018
Embargo Period
10-22-2018
Major Advisor
Dr. Guoan Zheng
Associate Advisor
Dr. Kazunori Hoshino
Associate Advisor
Dr. Patrick D. Kumavor
Field of Study
Biomedical Engineering
Degree
Doctor of Philosophy
Open Access
Open Access
Abstract
Optical microscope is an important tool for researchers to study small objects. In this thesis, we will focus on the improvement of traditional microscope systems from several aspects including resolution, field of view, speed, cost, compactness, multimodality. In particular, we will investigate computational imaging methods that bypass the limitations with traditional microscope systems by combining the optical hardware design and image processing algorithm. Examples will include optimizing illumination strategy for the Fourier ptychography (FP), developing field-portable high-resolution microscope using a cellphone lens, investigating pattern-illuminated FP for fluorescence microscopy, demonstrating multimodal microscopic imaging with the use of liquid crystal display, achieving fast and accurate autofocusing for whole slide imaging system.
Recommended Citation
Guo, Kaikai, "Development of Microscopy Systems for Super-Resolution, Whole-Slide, Hyperspectral, and Confocal Imaging" (2018). Doctoral Dissertations. 1751.
https://digitalcommons.lib.uconn.edu/dissertations/1751