Date of Completion
Lakshmi S. Nair
Biological Engineering | Biomaterials | Biomedical | Biomedical Devices and Instrumentation | Electrical and Electronics | Equipment and Supplies | Hardware Systems | Medical Biotechnology | Molecular, Cellular, and Tissue Engineering | Systems and Integrative Engineering | Therapeutics
Hydrogels are useful in wound healing, drug delivery, and tissue engineering applications, but the available methods of injecting them quickly and noninvasively are limited. The medical industry does not yet have access to an all-purpose device that can quickly synthesize hydrogels of different shapes and sizes. Many synthesis procedures that have been developed result in the formation of amorphous hydrogels. While generally useful, amorphous hydrogels exhibit limited capability in tissue engineering applications, especially due to their viscous properties. This endeavor aims to modulate the appropriate gelation parameters, optimize the injection process, and create a prototype that allows for the extrusion of uniformly mixed precursor gelation solutions. It involves the designing and testing of a hydrogel applicator that is capable of quickly dispensing hydrogels of predefined shapes onto a wound for enhanced healing. Said hydrogels can also be used in applications such as tissue engineering, regenerative medicine, and drug delivery.
Dunkle, Thomas; Deschamps, Jessica; and Dam, Connie, "Design and Development of Two Component Hydrogel Ejector for Three-Dimensional Cell Growth" (2015). Honors Scholar Theses. 416.
Biological Engineering Commons, Biomaterials Commons, Biomedical Commons, Biomedical Devices and Instrumentation Commons, Electrical and Electronics Commons, Equipment and Supplies Commons, Hardware Systems Commons, Medical Biotechnology Commons, Molecular, Cellular, and Tissue Engineering Commons, Systems and Integrative Engineering Commons, Therapeutics Commons